NHS information about the medicine lisinopril, including what it's used for, who can take it, how to take it and side effects. Lisinopril is an ACE inhibitor used in the treatment of hypertension, heart failure, and acute myocardial infarction (heart attack). Lisinopril is a medication belonging to the drug class of angiotensin-converting enzyme (ACE) inhibitors and is used to treat hypertension (high blood pressure), heart failure, and heart attacks. [7] For high blood pressure it is usually a first-line treatment. It is also used to prevent kidney problems in people with diabetes mellitus. [7] Lisinopril is an ACE inhibitor. It is used to treat high blood pressure, congestive heart failure in adults, or to improve survival after a heart attack. Lisinopril is an oral medication used to treat high blood pressure and heart failure. Learn about side effects, warnings, dosage, and more. Find patient medical information for Lisinopril (Prinivil, Zestril, others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Lisinopril is used alone or in combination with other medications to treat high blood pressure in adults and children 6 years of age and older. It is used in combination with other medications to treat heart failure. Lisinopril is also used to improve survival after a heart attack. Lisinopril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by. Lisinopril is a prescription drug that belongs to a class of medications called angiotensin-converting enzyme (ACE) inhibitors. Lisinopril relaxes the blood vessels in your body, resulting in a lowering of blood pressure and less stress on your heart. It comes as an oral tablet and an oral solution that are both taken by mouth. The oral solution is available as a brand-name medication only. Lisinopril is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. Lisinopril (Zestril, Qbrelis) is an angiotensin-converting enzyme (ACE) inhibitor. It’s prescribed to treat high blood pressure, heart failure, and heart attacks. Common lisinopril side effects include low blood pressure, dizziness, and headache. Some people may experience a dry cough from lisinopril that requires them to stop taking it.